Urine Cytology

Urine Cytology

Urine Cytology Most of the time, the sample is collected as clean catch urine sample in your doctor’s office or at home. This is done by urinating into a special container. The clean-catch method is used to prevent germs from the penis or vagina from getting into a urine sample. To collect your urine, the health care provider may give you a special clean-catch kit that contains a cleansing solution and sterile wipes. Follow instructions exactly so that the results are accurate. The urine sample can also be collected during cystoscopy. During this procedure, your health care provider uses a thin tube-like instrument with a camera on the end to examine the inside of your bladder. The urine sample is sent to a lab and examined under a microscope to look for abnormal cells. Source: http://www.nlm.nih.gov/medlineplus/ency/article/003905.htm Download Requisition...
FISH for Bladder Cancer

FISH for Bladder Cancer

FISH for Bladder Cancer UroVysion is a fluorescence in situ hybridization assay that was developed for the detection of bladder cancer in urine specimens. It consists of fluorescently labeled DNA probes to the pericentromeric regions of chromosomes 3 (red), 7 (green), and 17 (aqua) and to the 9p21 band (gold) location of the P16 tumor suppressor gene. The UroVysion assay works by detecting urinary cells that have chromosomal abnormalities consistent with a diagnosis of bladder cancer. Studies have shown that UroVysion is more sensitive than urine cytology for the detection of all stages and grades of bladder cancer. UroVysion is Food and Drug Administration-approved for the detection of recurrent bladder cancer in voided urine specimens from patients with a history of bladder cancer and for the detection of bladder cancer in voided urine specimens from patients with gross or microscopic hematuria, but no previous history of bladder cancer. Recent studies also suggest that UroVysion may be useful for assessing superficial bladder cancer patients’ response to bacillus Calmette-Guerin therapy and in detecting upper tract urothelial carcinoma. Source: http://www.ncbi.nlm.nih.gov/pubmed/18724101 Download Requisition...